Translation of Opiate Overdose Prevention Strategies (The OPT-IN Project)
In this study, we will use information gathered from potential interventionists at public health and healthcare settings to combine naloxone distribution practices with the BOS intervention and develop an online “toolkit” designed to facilitate translation into practice. Staff at partner organizations will then use the toolkit to deliver the combined interventions to their clients who are at risk of experiencing or witnessing an overdose. Our core partner is the Washtenaw County Health Initiative’s Opioid Project, which includes members across diverse settings (e.g., HIV outreach programs, shelters, addiction treatment, county health department, emergency departments). This project will use the translation framework of Enhanced Replicating Effective Programs (REP),12-14 which includes an online tool-kit package, the provision of training, and an external facilitator.
Aim 2: Pilot test the BOS + naloxone distribution toolkit combined with external facilitation as a strategy to aid translation to delivery by staff. Staff at three sites (a HIV outreach organization, a homeless shelter, and an emergency department) will use the online “toolkit” developed in Aim 1 to deliver the interventions to their clients/patients, with the help of an external facilitator and training, including technical support. We will evaluate the translation strategy using the RE-AIM framework,15 which includes Reach (e.g., number of individuals receiving intervention), Effectiveness (e.g., patient/client outcomes), Adoption (e.g., numbers trained), Implementation (e.g., fidelity of intervention delivery) and Maintenance (e.g., sustained in routine practice over time) with mixed qualitative and quantitative methods with interventionists and intervention recipients.
Findings from this study will set the stage for a future large-scale hybrid effectiveness-implementation trial. Ultimately, this work has high potential to have a meaningful effect on reducing the public health crisis of opioid overdose nationally by translating efficacious interventions to practice.